Healthcare

L-HPC/NBD

Multifunctional excipient for oral solid dose

L-HPC/NBD
L-HPC is a non-ionic multi-functional excipient

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) was first approved in 1977 as a disintegrant for tablets in Japan. In addition to the conventional grades (LH-), NBD- grades which have improved characteristics such as particle shape and compressibility were introduced in 2011.

L-HPC is a non-ionic multi-functional excipient, showing swelling properties in water.
Typical applications of L-HPC/NBD are anti-capping for tableting process, binder and disintegrant, stability enhancer of solid dosage forms. Several grades are available depending on application.

L-HPC grades

GradesDescriptionRegulatoryOriginKnowledge Base
LH-1150 µm, 11 % HPONF, EP, JPJapan Select
Related documentsLanguagesAvailable as Download or Request
Brochures
Guide to Applications
L-HPC
Pharmaceutical Excipients
Safety Data Sheets
Safety Data Sheet
LH-21. 2245 µm, 8-11 % HPONF, EP, JPJapan Select
Related documentsLanguagesAvailable as Download or Request
Brochures
Guide to Applications
L-HPC
Pharmaceutical Excipients
Safety Data Sheets
Safety Data Sheet
LH-B150 µm, 11 % HPONF, EP, JPJapan Select
Related documentsLanguagesAvailable as Download or Request
Brochures
Guide to Applications
L-HPC
Pharmaceutical Excipients
Safety Data Sheets
Safety Data Sheet
LH-31. 3220 µm, 8-11 % HPONF, EP, JPJapan Select
Related documentsLanguagesAvailable as Download or Request
Brochures
Guide to Applications
L-HPC
Pharmaceutical Excipients
Safety Data Sheets
Safety Data Sheet
NBD-02045 µm, 14 % HPONF, EP, JPJapan Select
Related documentsLanguagesAvailable as Download or Request
Brochures
Guide to Applications
L-HPC
Pharmaceutical Excipients
Safety Data Sheets
Safety Data Sheet
NBD-02145 µm, 11 % HPONF, EP, JPJapan Select
Related documentsLanguagesAvailable as Download or Request
Brochures
Guide to Applications
L-HPC
Pharmaceutical Excipients
Safety Data Sheets
Safety Data Sheet
NBD-02245 µm, 8 % HPONF, EP, JPJapan Select
Related documentsLanguagesAvailable as Download or Request
Brochures
Guide to Applications
L-HPC
Pharmaceutical Excipients
Safety Data Sheets
Safety Data Sheet

Grades and applications

Application
 
Tablets & Pellets
Anti-capping
Dissolution improvement for WG
Disintegration improvement for WG
Binding for WG
Disintegration improvement for DC
Binding for DC
Binding for RC
Pellet Extrusion
Dissolution improvement from drug layer
ODT
Capsules
Capsule Shell
Dispersing Aid for capsule filling
L-HPC
LH-11LH-21. 22LH-B1LH-31. 32NBD-020NBD-021NBD-022
             
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• Suitable / •• Very Suitable

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