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QbD (Quality by Design) approach for the formulation of hydrophylic matrix tablets using METOLOSE® SR (Acetaminophen) [SR-014]

In this study, the effects of METOLOSE® SR properties on in vitro drug release were investigated using QbD principles.

Comparative study of dissolutions from matrix tablets with METOLOSE® SR by different preparation methods [SR-012]

In this study, using theophylline as a model drug, dissolution profiles of matrix tablet which were prepared with same formulation by the different methods were compared.

The effect of glidant of hydrophilic matrix tablets containing METOLOSE® SR [SR-015]

In this study, theophylline which has poor flowability was selected as a drug model, a glidant (colloidal silicon dioxide) was added to the formulation containing METOLOSE® SR. The powder flowability…

METOLOSE® SR in 500 mg HCl extended release tablets: simulation of high speed compaction [SR-016]

In this study, we demonstrated the application of high viscous hypromellose METOLOSE® SR in a high speed tablet compression simulation of metformin HCl sustained release tablets.

Formulation of paracetamol bilayer tablet (dose: 650 mg) [SR-017]

The porpuse of this study was to formulate a paracetamol sustained release (SR) tablets 650 mg which will comply with the USP dissolution specification, keeping all other tablet parameters at desired…

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