In this study, a new aqueous coating formulation based on partial neutralization with amino-acid for mini-tablets with diameter of 3 mm has been introduced.
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Enteric coating agents are commonly used as aqueous dispersions for aqueous coating process as they are insoluble in purified water. Take a look at Part 1 as well.
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In this study, an amino acid, L-arginine was used to partially neutralize HPMCAS, which provided a stable dispersion in combination with the plasticizer.
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In this study, we introduce an optimized formulation with improved heat coagulation stability and process conditions for coating equipment from three different manufacturers.
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This study compares the enteric coating of mini-tablets using Shin-Etsu AQOAT® (HPMCAS) in perforated pan and fluid bed wurster typ processes.
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