The objective of this study was to assess the effect of hot melt extrusion (HME) on the physiochemical properties of HPMCAS
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Solid dispersions of Nifedipine (DP) using HPMCAS were prepared by hot-melt extrusion (HME) and evaluated.
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Typical alkali solutions such as sodium bicarbonate and sodium hydroxide were studied to select cleaning media to use after a coating operation with Shin-Etsu AQOAT® (HPMCAS).
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In this study, a solid dispersion preparation method using Shin-Etsu AQOAT® (HPMCAS) as a carrier is introduced, along with its application to solid dosage forms.
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The following data shows an example of enteric coating of hard gelatin capsules using Shin-Etsu AQOAT® (HPMCAS).
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